Zebra ZD421-HC is a 4-inch healthcare desktop barcode printer for patient identification, laboratory samples, pharmacy labels, healthcare assets and compliance labelling workflows.
- Healthcare white housing, disinfectant-ready plastics and sealed button interface
- 203 / 300 dpi, up to 6 ips and multiple 4-inch media choices
- USB / USB Host plus selectable Ethernet, Serial and Wi-Fi / Bluetooth configurations
- Description
- Additional information
- Part Number
- Accessories / Consumables
- Resources
- Certificates
- Video
- FAQ

Healthcare Barcode Printer / Zebra ZD421-HC
Zebra ZD421-HC Healthcare Desktop Barcode Printer
The Zebra ZD421-HC is a 4-inch healthcare desktop printer for clinical, laboratory, pharmacy and healthcare identification workflows. It supports direct thermal, thermal transfer roll and ribbon cartridge configurations, 203 / 300 dpi options, USB / USB Host and selectable wired or wireless connectivity. Its healthcare-focused design includes a white housing, disinfectant-ready plastics, sealed button interface and an IEC 60601-1 certified power supply.
Product Overview
A 4-inch desktop printer built for healthcare labelling workflows
The ZD421-HC is designed for healthcare teams that need a dependable desktop printer while still checking cleaning, power, label durability, ribbon handling and IT deployment requirements. Clinics, laboratories, pharmacies and healthcare operations can choose direct thermal, thermal transfer roll or ribbon cartridge models according to the label life and workflow. Before ordering, buyers should confirm print method, resolution, media size, connectivity, cutter or peeler needs, power supply and the exact Zebra Part Number.
Quick Fit
Is ZD421-HC the right fit?
Use this as a first screen before checking the final configuration and Part Number.
Good fit
4-inch healthcare labels, patient or sample identification, pharmacy labels, compliance labels and cleanable clinical work areas.
Confirm first
Print method, 203 / 300 dpi, USB / Ethernet / Serial / Wi-Fi, cutter, peeler, battery, ribbon cartridge and regional power options.
May not fit
Very high-volume industrial lines, labels wider than 4 inches, metal-frame industrial environments or built-in RFID encoding needs.
Suitable / Not Suitable
Best-fit and caution scenarios
Suitable
- Clinical, laboratory, pharmacy, patient identification, sample identification, shelf and compliance labelling.
- Workflows that need healthcare-preferred white housing, disinfectant-ready plastics, UV-resistant housing and IEC 60601-1 certified power supply.
- Sites that need a single healthcare printer family with direct thermal, thermal transfer roll and ribbon cartridge choices.
Check alternatives
- High-volume industrial lines should compare Zebra industrial printers.
- RFID encoding is not confirmed as a standard ZD421-HC feature in the current official source set.
- Warranty term, stock status, sellable regional Part Numbers and healthcare documentation should be confirmed before ordering.
Key Features
Key ZD421-HC capabilities
Healthcare housing
White healthcare colour scheme, disinfectant-ready plastics, UV-resistant housing and sealed button interface.
IEC 60601-1 power
Healthcare models include an IEC 60601-1 certified power supply for healthcare facility requirements.
Three print configurations
Direct thermal, thermal transfer roll and ribbon cartridge models cover different label durability and operation needs.
203 / 300 dpi
203 dpi for general 4-inch labels; 300 dpi for finer text, denser barcodes or higher readability requirements.
Up to 6 ips
Up to 6 ips at 203 dpi and up to 4 ips at 300 dpi for desktop-class healthcare labelling.
Flexible connectivity
USB / USB Host standard, with Ethernet, Serial and Wi-Fi / Bluetooth options depending on configuration.
Print DNA / Link-OS
Supports Link-OS, ZPL II, EPL 2, PDF Direct and Zebra Print DNA software tools.
Media handling options
Dispenser / peeler, cutter, battery, carrying case, ZKDU and media core adapter options are available to check.
Applications
Common healthcare and B2B uses
Patient and record ID
Labels and identification workflows for patient records, wristbands or department-level tracking.
Laboratory samples
Sample identification and track-and-trace workflows where readability and consistent label formats matter.
Pharmacy labels
Medication, product and compliance labels where material and ribbon choices should be tested.
Healthcare assets
Labels for supplies, shelves, equipment, storage areas and internal healthcare assets.
Accessories / Consumables / Software
Check supplies, accessories and software together
A ZD421-HC purchase should include the printer, labels, ribbons where applicable, printheads, platen rollers, cutter or peeler modules, wireless modules, power supply, Zebra Setup Utilities, ZebraDesigner, Windows driver, ZPL / EPL output and Zebra OneCare options. Easy Scan can help Hong Kong buyers map these requirements before selecting a sellable Part Number.
Selection Guide
Information to prepare before enquiry
- Label use case: patient ID, sample labels, pharmacy, shelf, asset, compliance or product labels.
- Label size and material: width, length, paper or synthetic media, wristband need and cleaning exposure.
- Print method: direct thermal for shorter-life labels; thermal transfer for longer-life labels; cartridge when simplified ribbon loading matters.
- Resolution: 203 dpi for general labels; 300 dpi for small text, dense barcodes or compact labels.
- Connectivity and mounting: USB, Ethernet, Serial, Wi-Fi / Bluetooth, desktop, cart, battery, cutter / peeler and power requirements.
Comparison
ZD421-HC configuration directions
| Configuration | Best fit | Buyer check |
|---|---|---|
| ZD421d-HC Direct Thermal | Shorter-life healthcare labels, wristbands and general identification labels without ribbon. | Confirm direct thermal media life and exposure conditions. |
| ZD421t-HC Thermal Transfer Roll | More durable labels for pharmacy, asset or longer-life applications. | Confirm ribbon width, media width, material and ribbon formulation. |
| ZD421c-HC Ribbon Cartridge | Teams that want faster ribbon changes and fewer ribbon-loading errors. | Confirm cartridge availability, media size and total consumable cost. |
| ZD411-HC | 2-inch healthcare labels and smaller workspaces. | Choose ZD421-HC when 4-inch label width is required. |
| Standard ZD421 | General non-healthcare desktop labelling. | Choose ZD421-HC when healthcare housing, sealed buttons or IEC 60601-1 power supply is required. |
Buying Pitfalls
Common mistakes to avoid
Treating HC as a standard ZD421
Healthcare models have specific housing, power and replacement-part considerations.
Skipping print-method selection
Direct thermal and thermal transfer choices affect label durability and consumables.
Buying the printer only
Labels, ribbons, printheads, cleaning process and barcode readability should be checked together.
Missing connectivity details
USB, Ethernet, Serial, Wi-Fi and Bluetooth options depend on the selected configuration or upgrade module.
Why Buy From Easy Scan
Why ask Easy Scan about ZD421-HC
Easy Scan is a Zebra Premier Solution Partner and can help Hong Kong healthcare and B2B buyers check ZD421-HC official information, healthcare configurations, Part Numbers, labels, ribbons, accessories, documentation and local procurement requirements before ordering.
Specifications
ZD421-HC specifications
The following is summarised from Zebra official product, specification sheet, technical specifications and user guide sources. Sellable configurations and regional Part Numbers should be confirmed at quotation stage.
| Product Positioning | |
|---|---|
| Product family | Zebra ZD421-HC, ZD400 Series healthcare desktop printers |
| Main model variants | ZD421d-HC direct thermal, ZD421t-HC thermal transfer roll, ZD421c-HC ribbon cartridge |
| Replaces | ZD420-HC, GK420, GT800 |
| Common uses | Track and trace, laboratory management, shelf and product labeling, compliance labeling, electronic patient and medical record access and identification |
| Print And System | |
| Print methods | Direct thermal, thermal transfer roll, thermal transfer cartridge |
| Print resolution | 203 dpi / 8 dots per mm; 300 dpi / 12 dots per mm optional |
| Maximum print width | 4.09 in. / 104 mm for 203 dpi; 4.27 in. / 108 mm for 300 dpi; cartridge 4.09 in. / 104 mm |
| Maximum print speed | 6 in. / 152 mm per second at 203 dpi; 4 in. / 102 mm per second at 300 dpi |
| Operating system | Link-OS |
| Memory | 512 MB Flash; 256 MB SDRAM; 64 MB user available non-volatile memory; 8 MB user available SDRAM |
| Firmware / languages | ZPL II; EPL 2; XML; ZBI; PDF Direct |
| Healthcare Design | |
| Housing | Healthcare-preferred white color scheme; disinfectant-ready, easy-to-clean plastics |
| Button interface | Sealed button interface |
| Cleaning support | UV-resistant housing supports UV cleaning protocols |
| Power supply | Healthcare models include IEC 60601-1 certified power supply |
| Real time clock | Real Time Clock (RTC) standard on healthcare models |
| Media And Ribbon | |
| Label length | Minimum 0.25 in. / 6.4 mm; maximum 39.0 in. / 991 mm |
| Media width | Direct thermal: 0.585-4.25 in. / 15-108 mm; thermal transfer roll: 0.585-4.41 in. / 15-112 mm; cartridge: 0.585-4.65 in. / 15-118 mm |
| Media roll size | Maximum outer diameter 5.00 in. / 127 mm; 0.5 in. and 1.0 in. core standard; 1.5, 2.0 and 3.0 in. with optional adapters |
| Media thickness | 0.003 in. / 0.08 mm min.; 0.0075 in. / 0.19 mm max. |
| Media types | Roll-fed or fan-fold, die cut or continuous with or without black mark, tag stock, continuous receipt paper and wristbands |
| Ribbon outside diameter | 2.6 in. / 66 mm for 300 m; 1.34 in. / 34 mm for 74 m |
| Ribbon length | Roll: 984 ft. / 300 m or 243 ft. / 74 m; cartridge: 243 ft. / 74 m |
| Ribbon width | Roll: 1.33-4.3 in. / 33.8-109.2 mm; cartridge: 4.3 in. / 109.2 mm |
| Connectivity And Options | |
| Standard connectivity | USB 2.0, USB Host, Bluetooth Low Energy for setup |
| Optional connectivity | Ethernet 10/100, Wi-Fi 802.11ac with Bluetooth 4.1, serial RS-232 auto-sensing DB-9; product page also lists Wi-Fi 6 with Bluetooth 5.3 as an optional configuration |
| Sensors | Full-width moveable reflective / black mark sensor; multi-position transmissive / gap sensor |
| Media handling | Field-installable dispenser / peeler and cutter |
| Other accessories | Battery, carrying case, Zebra Keyboard Display Unit, enclosed / attached power supply, mounting adapter plate, media core adapters |
| Dimensions And Environment | |
| Dimensions | Direct thermal: 8.69 x 6.98 x 5.93 in.; thermal transfer roll: 10.5 x 8.0 x 7.44 in.; cartridge: 10.0 x 8.0 x 7.0 in. |
| Weight | Direct thermal: 2.98 lb / 1.35 kg; thermal transfer roll: 4.52 lb / 2.05 kg; cartridge: 5.0 lb / 2.3 kg |
| Operating temperature | 40 to 105 F / 4.4 to 41 C |
| Storage temperature | -40 to 140 F / -40 to 60 C |
| Operating humidity | 10% to 90% non-condensing |
| Storage humidity | 5% to 95% non-condensing |
| Electrical | Auto-detectable 100-240 VAC, 50-60 Hz; ENERGY STAR certified; Energy Efficiency Level VI certified; optional 2750 mAh battery |
FAQ
Frequently Asked Questions
How is ZD421-HC different from a standard ZD421?
ZD421-HC is the healthcare version, with healthcare white housing, disinfectant-ready plastics, sealed button interface, UV-resistant housing and IEC 60601-1 certified power supply according to Zebra official sources.
Should I choose direct thermal, thermal transfer or ribbon cartridge?
Use direct thermal for shorter-life labels, thermal transfer for more durable labels, and ribbon cartridge when simplified ribbon replacement is important for frontline users.
Does every ZD421-HC include Wi-Fi?
No. Zebra lists wired and wireless options, but the actual interface set depends on the selected Part Number or upgrade module.
Talk To Easy Scan
Need help checking a Zebra ZD421-HC configuration?
Share your label use case, media size, print content, connectivity needs and operating environment. Easy Scan can help check the configuration, Part Number, consumables and documentation.
| Brand | Zebra |
|---|---|
| Product Type | Healthcare desktop barcode printer |
| Series | ZD400 Series |
| Model | ZD421-HC / ZD421d-HC / ZD421t-HC / ZD421c-HC |
| Printer Type | 4-inch desktop printer |
| Print Method | Direct thermal, thermal transfer roll, thermal transfer cartridge |
| Print Resolution | 203 dpi; 300 dpi |
| Max Print Width | 203 dpi: 4.09 in. / 104 mm; 300 dpi: 4.27 in. / 108 mm |
| Max Print Speed | 203 dpi: up to 6 ips / 152 mm/s; 300 dpi: up to 4 ips / 102 mm/s |
| RFID Support | Not confirmed as a standard function in current source set; confirm by selected Part Number |
| Connectivity | USB 2.0, USB Host; optional Ethernet 10/100, RS-232 Serial, Wi-Fi 802.11ac |
| Wireless Support | BLE for setup; optional Wi-Fi 802.11ac + Bluetooth 4.1 |
| Suitable Application | Clinical, laboratory, pharmacy, asset, compliance and retail label workflows; confirm final Part Number for exact use case |
| Replacement Path | Non-HC ZD421 line should be confirmed against procurement scope |
Part Number
Part Number
Zebra ZD421-HC Part Number
The Part Number and Description values below are for configuration checking. Sellable models, regional power bundles, interfaces and supply status should be confirmed at quotation stage.
ZD421d-HC direct thermal healthcare configurations
| Part Number | Description |
|---|---|
| ZD4AH42-D0PE00EZ | Direct Thermal Printer ZD421, Healthcare; 203 dpi, USB, USB Host, Ethernet, BTLE5, APAC Cord Bundle (EU, UK, AUS, JP), Swiss Font, EZPL |
ZD421t-HC thermal transfer healthcare configurations
| Part Number | Description |
|---|---|
| ZD4AH42-30GE00EZ | Thermal Transfer Printer (74/300M) ZD421, Healthcare; 203 dpi, USB, USB Host, Ethernet, BTLE5, India Cord, Swiss Font, EZPL |
| ZD4AH42-30PE00EZ | Thermal Transfer Printer (74/300M) ZD421, Healthcare; 203 dpi, USB, USB Host, Ethernet, BTLE5, APAC Cord Bundle (EU, UK, AUS, JP), Swiss Font, EZPL. |
| ZD4AH43-30GE00EZ | Thermal Transfer Printer (74/300M) ZD421, Healthcare; 300 dpi, USB, USB Host, Ethernet, BTLE5, India Cord, Swiss Font, EZPL |
| ZD4AH43-30PE00EZ | Thermal Transfer Printer (74/300M) ZD421, Healthcare; 300 dpi, USB, USB Host, Ethernet, BTLE5, APAC Cord bundle (EU, UK, AUS, JP), Swiss Font, EZPL |
ZD421c-HC ribbon cartridge healthcare configurations
| Part Number | Description |
|---|---|
| ZD4AH42-C0PE00EZ | Thermal Transfer Cartridge Printer ZD421, Healthcare; 203 dpi, USB, USB Host, Ethernet, BTLE5, APAC Cord bundle (EU, UK, AUS, JP), Swiss Font, EZPL |
Accessories / Consumables
Accessories / Consumables
ZD421-HC Accessories, Repair Parts And Services
The accessory, repair-part and service rows below are prepared for ZD421-HC configuration checks. Part Number and Description values are kept verbatim and should be checked against the final model, regional configuration and supply status.
Healthcare-specific power, covers and printheads
| Part Number | Description |
|---|---|
| P1079903-030 | Kit, Healthcare Power Supply, 75W, 24V with US cord, ZD410D, ZD420C, ZD420D, ZD420T, ZD620D, ZD620T,GK420, HC100, ZD510-HC, ZD421D, ZD421T, ZD421C, ZD621D, ZD621T |
| P1112640-026 | Kit, 203 dpi Printhead for Healthcare Models, ZD421D |
| P1112640-027 | Kit, 300 dpi printhead for Healthcare Models, ZD421D |
| P1112640-003 | Kit, Cover Assembly for Healthcare Models (white) includes Media Window, ZD421D |
| P1112640-006 | Kit, Inner Lid without printhead, healthcare models, ZD421D |
| P1112640-008 | Kit, Latch Assembly for Healthcare Models, ZD421D |
| P1112640-013 | Kit, Rear Bezels and Wifi Bezel for Healthcare Models, ZD421D |
| P1112640-024 | Kit, Nameplate for Healthcare Models, ZD421D |
| P1112640-039 | Kit, Control Panel PCBA without LCD. For Standard ZD621D Models, ZD621T Models and Healthcare ZD421D Models |
| P1112640-203 | Kit, Cover Assembly for Healthcare Models, ZD421T |
| P1112640-213 | Kit, Rear Bezels and WiFi Bezel for Healthcare Models, ZD421T |
| P1112640-215 | Kit, Front Bezel for Healthcare Models, ZD421T |
| P1116110-003 | Kit, Cover Assembly for Healthcare Models, ZD421C |
Connectivity, power and media-handling kits
| Part Number | Description |
|---|---|
| 105934-053 | Kit, Power Supply, 60W, 24V, USA Cord and EU Cord, GK420D, GK420T, GT800, ZD410D, ZD421D, ZD421T |
| P1079903-026 | KIT, POWER SUPPLY, 75W, 24V, US Cord, EU Cord, GX420D, GX420T, GK888E, GK420E, GX430T, ZD410D, ZD420C, ZD420D, ZD420T, ZD500, ZD500R, ZD620D, ZD620T, ZD421C, ZD621D, ZD621T, ZD621R |
| P1080383-234 | Kit Attached Power Supply ZD420T ZD620T, ZD621T, ZD621R, ZD421C |
| P1112640-057 | Kit, Attached Power Supply, 60W, ZD421D, Standard Model |
| P1112640-248 | Kit, Attached Power Supply, 60W, ZD421T, Standard Model |
| P1112640-015 | Kit, Ethernet Module, ZD421D, ZD421T, ZD421C, ZD411D, ZD411T, ZD611D, ZD611T |
| P1112640-016 | Kit, Serial Module, ZD421D, ZD421T, ZD421C, ZD411D, ZD411T, ZD611D, ZD611T |
| P1112640-017A | Kit, Wireless Module, WiFi 802.11ac, MFI 3.0, Bluetooth 4.1, USA & Canada, ZD421D, ZD621D, ZD421T, ZD411D, ZD411T, ZD611D, ZD611T |
| P1112640-017B | Kit, Wireless Module, WiFi 802.11ac, MFI 3.0, Bluetooth 4.1, Japan, ZD421D, ZD621D, ZD421T, ZD411D, ZD411T, ZD611D, ZD611T |
| P1112640-017C | Kit, Wireless Module, WiFi 802.11ac, MFI 3.0, Bluetooth 4.1, All countries except USA, Canada and Japan, ZD421D, ZD621D, ZD421T, ZD411D, ZD411T, ZD611D, ZD611T |
| P1112640-239B | Kit, Wireless Module, WiFi 802.11ac, MFI 3.0, Bluetooth 4.1, Japan, ZD621T, ZD421C, ZD621R |
| P1112640-239C | Kit, Wireless Module, WiFi 802.11ac, MFI 3.0, Bluetooth 4.1, All countries except USA, Canada and Japan, ZD621T, ZD421C |
| P1080383-022 | Kit, Media Core Adaptors for 1.5, 2 & 3 Diameter Media Cores, (set of 2 each), ZD420C, ZD420T, ZD620T, ZD621T, ZD421C, ZD621R, ZD421C, ZD621T, ZD621T-R |
| P1112640-054 | Kit, Media Core Adaptors for 1.5, 2 & 3 Diameter Media Cores, (set of 2 each), ZD411D, ZD411T, ZD611D, ZD611T, ZD611T-R, ZD421C, ZD421D, ZD421T, ZD621D, ZD621T, ZD621T-R |
| P1112640-030 | Kit, Upgrade, Cutter, ZD421D, ZD621D |
| P1112640-230 | Kit, Upgrade, Cutter, ZD421T |
| P1112640-345 | Kit, Upgrade, Partial Cutter, ZD421D, ZD621D |
| P1112640-031 | Kit, Upgrade, Dispenser, ZD421D, ZD621D |
| P1112640-231 | Kit, Upgrade, Dispenser, ZD421T |
| P1112640-233 | Kit, Upgrade, Dispenser, ZD621T, ZD421C |
Printheads, platen rollers and repair parts
| Part Number | Description |
|---|---|
| P1112640-061 | Kit, Platen Roller 203 dpi, ZD421D, ZD621D |
| P1112640-062 | Kit, Platen Roller 300 dpi, ZD421D, ZD621D |
| P1112640-216 | Kit, Platen Roller 203 dpi, ZD421T |
| P1112640-217 | Kit, Platen Roller 300 dpi, ZD421T |
| P1116110-015 | Kit, Platen Roller 300 dpi, ZD421 Cartridge |
| P1112640-019 | Kit, 203 dpi Printhead for Standard Models, ZD421D |
| P1112640-020 | Kit, 300 dpi printhead for Standard Models, ZD421D |
| P1112640-218 | Kit, Printhead 203 dpi, ZD421T |
| P1112640-219 | Kit, Printhead 300 dpi, ZD421T |
| P1116110-009 | Kit, Printhead 203dpi, ZD421C |
| P1116110-010 | Kit, Printhead 300dpi, ZD421C |
| P1080383-015 | Kit, Motor Assy, ZD420C, ZD421C |
| P1080383-023 | Kit, Cover Hinge, ZD420C, ZD421C |
| P1112640-001 | Kit, Nameplate, ZD421D |
| P1112640-002 | Kit, Cover Assembly for Standard Models includes Media Window, ZD421D |
| P1112640-004 | Kit, Control Panel PCBA without LCD, ZD421D, ZD421T |
| P1112640-005 | Kit, Inner Lid without printhead, standard models, ZD421D |
| P1112640-007 | Kit, Latch Assembly for Standard Models, ZD421D |
| P1112640-009 | Kit, Upper Media Sensor (Gap Sensor), ZD421D, ZD621D |
| P1112640-010 | Kit, Print Mechanism 203dpi, ZD421D |
| P1112640-011 | Kit, Print Mechanism 300dpi, ZD421D |
| P1112640-012 | Kit, Lower Media Sensor, (black line sensor), ZD421D, ZD621D |
| P1112640-014 | Kit, Main Logic Board USB, USB Host, Bluetooth, Modular Connectivity Slot, ZD421D, ZD621D, ZD421T, ZD621T |
| P1112640-018 | Kit, Front Bezel, Standard, ZD421D ZD621D |
| P1112640-025 | Kit, Rear Bezels and Wifi Bezel for Standard Models, ZD421D |
| P1112640-043 | Kit, Cover for Hinge, ZD421D, ZD621D |
| P1112640-058 | Kit, Head Open Sensor, ZD421D, ZD621D |
| P1112640-070 | Kit, Main Logic Board USB, USB Host, Bluetooth, Modular Connectivity Slot, the board included in this kit allows firmware downgrades to occur, ZD421D, ZD621D, ZD421T, ZD621T, ZD621R |
| P1112640-110 | Kit, Lower frame with Gears 203dpi, ZD421D |
| P1112640-111 | Kit, Lower frame with Gears 300dpi, ZD421D |
| P1112640-200 | Kit, Media Window, ZD421T |
| P1112640-202 | Kit, Cover Assembly for Standard Models, ZD421T |
| P1112640-204 | Kit, Ribbon Out Sensor, ZD421T |
| P1112640-205 | Kit, Latch Assembly, ZD421T |
| P1112640-206 | Kit, Ribbon Carriage, ZD421T |
| P1112640-207 | Kit, Upper Media Sensor (moveable gap sensor), ZD421T ZD621T |
| P1112640-208 | Kit, Print Mechanism 203dpi, ZD421T |
| P1112640-209 | Kit, Print Mechanism 300dpi, ZD421T |
| P1112640-210 | Kit, Head Open Sensor, ZD421T |
| P1112640-211 | Kit, Blackline Sensor, Movable, ZD421T |
| P1112640-212 | Kit, Rear Bezels and WiFi Bezel for Standard Models, ZD421T |
| P1112640-214 | Kit, Front Bezel for Standard Models, ZD421T |
| P1112640-245 | Kit, Front Bezel, ZD621T, ZD421C |
| P1112640-249 | Kit, Shipping Pack, ZD421T, ZD621T, ZD621T-R |
| P1112640-254 | Kit, Nameplate, ZD421T |
| P1116110-001 | Kit, Nameplate, ZD421C |
| P1116110-002 | Kit, Cover Assembly for Standard Models, ZD421C |
| P1116110-004 | Kit, Ribbon Out Sensor, ZD421C |
| P1116110-005 | Kit, Ribbon Carriage, ZD421C |
| P1116110-006 | Kit, Upper Media Sensor, ZD421C |
| P1116110-007 | Kit, Print Mechanism, ZD421C |
| P1116110-008 | Kit, Lower Media Sensor, ZD421C |
| P1116110-014 | Kit, Platen Roller 203 dpi, ZD421 Cartridge |
| P1116110-025 | Kit, Upgrade, Cutter, ZD421C |
Zebra OneCare and support services
| Part Number | Description |
|---|---|
| Z1AE-ZD4X1-3C0 | Zebra OneCare, Essential, Purchased within 30 days of Device, ZD411d,ZD411t, ZD421d, ZD421t, ZD421c, 3 Years, Comprehensive |
| Z1AE-ZD4X1-5C0 | Zebra OneCare, Essential, Purchased within 30 days of Device, ZD411d,ZD411t, ZD421d, ZD421t, ZD421c, 5 Years, Comprehensive |
| Z1AP-ZD4X1-3C0 | PRS Parts Agreements, 3 yr, ZD411, ZD421, Purchased within 30 days of Printer, UK, India, SEA, Japan, non-EU EEME, NOLA, SOLA, BR Only, Not available Korea, MX, Comprehensive |
| Z1AP-ZD4X1-5C0 | PRS Parts Agreements, 5 yr, ZD411, ZD421, Purchased within 30 days of Printer, UK, India, SEA, Japan, non-EU EEME, NOLA, SOLA, BR Only, Not available Korea, MX, Comprehensive |
| Z1AS-ZD4X1-3C0 | 3 yr Z1C Select, ZD4X1, advanced replacement, Not avail in LATAM / req's Customer owned buffer in NA / Zebra owned buffer in EMEA & APAC, purchased in 30 days, comprehensive, printheads covered (Model-ZD411d,ZD411t, ZD421d, ZD421t, ZD421c) |
| Z1AS-ZD4X1-5C0 | 5 yr Z1C Select, ZD4X1, advanced replacement, Not avail in LATAM / req's Customer owned buffer in NA / Zebra owned buffer in EMEA & APAC, purchased in 30 days, comprehensive, printheads covered (Model-ZD411d,ZD411t, ZD421d, ZD421t, ZD421c) |
| Z1BE-ZD4X1-1C0 | Zebra OneCare, Essential, Purchased after 30 days of Device, ZD411d,ZD411t, ZD421d, ZD421t, ZD421c, 1 Years, Comprehensive |
| Z1BE-ZD4X1-3C0 | Zebra OneCare, Essential, Purchased after 30 days of Device, ZD411d,ZD411t, ZD421d, ZD421t, ZD421c, 3 Years, Comprehensive |
| Z1BP-ZD4X1-1C0 | PRS Parts Agreements, 1 yr, ZD411, ZD421, Purchased after 30 days of Printer, UK, India, SEA, Japan, non-EU EEME, NOLA, SOLA, BR Only, Not available Korea, MX, Comprehensive |
| Z1BP-ZD4X1-3C0 | PRS Parts Agreements, 3 yr, ZD411, ZD421, Purchased after 30 days of Printer, UK, India, SEA, Japan, non-EU EEME, NOLA, SOLA, BR Only, Not available Korea, MX, Comprehensive |
| Z1BS-ZD4X1-3C0 | 3 yr Z1C Select, ZD4X1, advanced replacement, Not avail in LATAM/req's Customer owned buffer in NA / Zebra owned buffer in EMEA & APAC, purchased after 30 days, comprehensive, printheads covered (Model-ZD411d,ZD411t, ZD421d, ZD421t, ZD421c) |
| Z1RE-ZD4X1-1C0 | Zebra OneCare, Essential, Renewal, ZD411d,ZD411t, ZD421d, ZD421t, ZD421c, 1 Years, Comprehensive |
| Z1RE-ZD4X1-2C0 | Zebra OneCare, Essential, Renewal, ZD411d,ZD411t, ZD421d, ZD421t, ZD421c, 2 Years, Comprehensive |
| Z1RP-ZD4X1-1C0 | PRS Parts Agreements, 1 yr, ZD411, ZD421, Renewal, UK, India, SEA, Japan, non-EU EEME, NOLA, SOLA, BR Only, Not available Korea, MX, Comprehensive |
| Z1RP-ZD4X1-2C0 | PRS Parts Agreements, 2 yr, ZD411, ZD421, Renewal, UK, India, SEA, Japan, non-EU EEME, NOLA, SOLA, BR Only, Not available Korea, MX, Comprehensive |
| Z1RS-ZD4X1-1C0 | 1 yr Z1C Select, ZD4X1, advanced replacement, Not avail in LATAM / requires Customer owned buffer in NA / Zebra owned buffer in EMEA & APAC, Renewal, comprehensive, includes printhead coverage (Model-ZD411d,ZD411t, ZD421d, ZD421t, ZD421c) |
| Z1RS-ZD4X1-2C0 | 2 yr Z1C Select, ZD4X1, advanced replacement, Not avail in LATAM / requires Customer owned buffer in NA / Zebra owned buffer in EMEA & APAC, Renewal, comprehensive, includes printhead coverage (Model-ZD411d,ZD411t, ZD421d, ZD421t, ZD421c) |
Resources
Resources
ZD421-HC Official Resources
Certificates
Certificates
Zebra Premier Solution Partner Proof
Easy Scan is a Zebra Premier Solution Partner and can help Hong Kong healthcare and B2B buyers check ZD421-HC configurations, Part Numbers, consumables, documentation and local procurement requirements.
Video
Video
Zebra ZD421-HC / ZD421 Official Videos
These videos cover the ZD421 series, connectivity, Print Touch, media adapters, calibration, media changes and the battery option.

Introducing the ZD421 Desktop Printers | Zebra
Introduces the ZD421 desktop printer series.

How to Set Up WiFi/Bluetooth Connectivity for the ZD421 and ZD621 Printers | Zebra
Shows ZD421 / ZD621 Wi-Fi and Bluetooth setup.

ZD411/ZD421/ZD611/ZD621 Using the Print Touch Feature | Zebra
Shows how to use the Print Touch feature.

ZD411/ZD421/ZD611/ZD621 Installing the Optional Media Adapter | Zebra
Shows optional media adapter installation.

ZD411/ZD421/ZD611/ZD621 Manual Media Calibration | Zebra
Shows the manual media calibration workflow.

ZD411/ZD421/ZD611/ZD621 Changing Media | Zebra
Shows the media change workflow.

ZD411/ZD421/ZD611/ZD621 Using the Battery Option | Zebra
Shows how the battery option is used.
FAQ
FAQ
Zebra ZD421-HC FAQ
Is ZD421-HC suitable for healthcare environments?
Zebra official sources describe ZD421-HC as built specifically for healthcare environments, with healthcare white housing, disinfectant-ready plastics, sealed button interface, UV-resistant housing and IEC 60601-1 certified power supply.
Does it need ribbon?
ZD421d-HC direct thermal does not use ribbon. ZD421t-HC thermal transfer roll and ZD421c-HC ribbon cartridge models need ribbon or cartridge selection according to label material and durability.
Is 300 dpi required?
Not always. 203 dpi is suitable for many 4-inch labels; 300 dpi should be checked for small text, compact labels, dense barcodes or higher readability needs.
Can cutter or peeler options be added?
Zebra lists field-installable cutter and dispenser / peeler options. The actual configuration and compatible Part Number should be confirmed before ordering.
Are healthcare parts the same as standard ZD421 parts?
Some parts are shared and some are healthcare-specific. Local PN data includes healthcare power supply, healthcare printheads and healthcare covers, so exact model and Part Number checking is important.
How can Easy Scan help?
Easy Scan can help check use case, media size, print method, supplies, connectivity, accessories, Part Numbers, documentation and Hong Kong B2B procurement requirements.
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